A critical review of palladium organometallic anticancer agents
نویسندگان
چکیده
With the aim of overcoming well-known limitations platinum-based antineoplastic drugs, recent efforts have focused on development new anticancer agents containing metals other than platinum. Among these agents, organopalladium compounds received significant attention due to their generally high stability under physiological conditions. A number shown promising in vitro and vivo antiproliferative activity toward several cisplatin-sensitive cisplatin-resistant tumors sometimes exhibited a different mechanism action compared drugs. In this review, advances field as potential are discussed.
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ژورنال
عنوان ژورنال: Cell reports physical science
سال: 2021
ISSN: ['2666-3864']
DOI: https://doi.org/10.1016/j.xcrp.2021.100446